jPlayer is a lightweight (8kb minified and gzipped) audio and video jQuery plugin for HTML5.
It is cross browser compatible and also works on iOS, Android, Blackberry mobile devices.
It supports mp3, mp4 (AAC/H.264), ogg(Vorbis/Theora), webm(Vorbis/VP8), wav, flv media.
There is a comprehensive API and support is provided by an active community.
Multiple instances of the player can be included on the same page. The player itself is themeable and two themes are provided.
It is also possible to create a playlist and add it to the player.